Under-Eye Polynucleotides Compared: Vitaran I, LUMI-PRO Eyes and AETER Puri Eyes Pro

The periocular area is thin, mobile and unforgiving, which is why polynucleotide boosters formulated specifically for the eyes have become a category of their own. We stock three, and on paper they look similar. The differences that actually matter are concentration, whether hyaluronic acid is included, and how many syringes you get for the price. Here is how they compare, based on the specifications on each product page.

Vitaran I

Vitaran I is a CE-marked polynucleotide injectable for the delicate eye area, formulated with highly purified fragments derived from trout DNA. Its composition is polynucleotide sodium at 20mg/ml, described as PN 2%, and it is supplied as 2 x 1ml pre-filled syringes.

The listing describes it as supporting collagen and elastin production and the skin's natural barrier, helping improve the appearance of periocular lines and wrinkles, firmness, elasticity and radiance, alongside antioxidant and anti-inflammatory properties. It is the highest-concentration option of the three and the only one supplied as a two-syringe pack.

LUMI-PRO Eyes

LUMI-PRO Eyes is a polynucleotide skin booster containing 5mg/ml of polynucleotides, aimed at dark under-eye circles, puffiness and fine wrinkles. The listing describes it as hydrating and revitalising the under-eye area, with the polynucleotide component supporting cell repair and collagen production.

It is the lightest concentration of the three, which suits practitioners who prefer a gentler starting point in a delicate area or who are building up over a course.

AETER Puri Eyes Pro

AETER Puri Eyes Pro is the only one of the three that pairs polynucleotides with hyaluronic acid. It contains 6mg of medical-grade polynucleotides plus HA, so you get the skin-renewal action of PN alongside the moisture-binding effect of hyaluronic acid in a single product.

The manufacturer describes the concentrated formula as three times stronger than the standard AETER Puri Eyes, positioning it as the more intensive option in that brand's eye range. The listing covers fine lines and wrinkles, collagen and elastin support, firmness, hydration and the appearance of dark circles.

How to choose between them

Concentration is the clearest dividing line. Vitaran I sits well above the other two at 20mg/ml, LUMI-PRO Eyes is the lightest at 5mg/ml, and AETER Puri Eyes Pro sits at 6mg of PN but adds hyaluronic acid to the mix. A higher PN figure is not automatically the right choice for every client or every eye area; it is a clinical judgement based on skin quality, the client's history and how you plan the course.

Formulation is the second consideration. If a client's main concern is crepiness and hydration as much as skin quality, the PN and HA combination in AETER Puri Eyes Pro gives you both in one syringe. If you would rather keep polynucleotides pure and control hydration separately, Vitaran I or LUMI-PRO Eyes keeps that separation.

Then there is pack contents, which quietly changes the maths. Vitaran I is supplied as two 1ml syringes, so compare it per syringe rather than per box when you are costing a course against the single-syringe options.

Treatment technique, dosage and scheduling all depend on an individual clinical assessment, and a course may involve multiple sessions. Check the manufacturer's official instructions for use for each product rather than applying one protocol across all three.

Important information

All products mentioned here are for professional use only and must be administered by an appropriately trained and qualified medical professional. Suitability, placement and dosage require an individual clinical assessment, and clients should receive a full consultation before treatment. Always follow the manufacturer's official instructions for use.